Language comes naturally to us, but is also deeply mysterious. On the one hand, it manifests as a collection of sounds or marks on paper. On the other hand, it also conveys meaning – words and sentences refer to states of affairs in the outside world, or to much more abstract concepts. How do words and meaning come together in the brain? David Poeppel is a leading neuroscientist who works in many areas, with a focus on the relationship between language and thought. We talk about cutting-edge ideas in the science and philosophy of language, and how researchers have just recently climbed out from under a nineteenth-century paradigm for understanding how all this works. David Poeppel is a Professor of Psychology and Neural Science at NYU, as well as the Director of the Max Planck Institute for Empirical Aesthetics in Frankfurt, Germany. He received his Ph.D. in cognitive science from MIT. He is a Fellow of the American Association of Arts and Sciences, and was awarded the DaimlerChrysler Berlin Prize in 2004. He is the author, with Greg Hickok, of the dual-stream model of language processing.